Leaving the Books Behind -- Preservation Woes

Leaving the Past Behind

There is considerable interest from the wider scientific community in the heritability of epigenetic states across generations, and this has arisen as a result of a series of studies in mice [1,2], flies [3], plants [4,5], and yeast [6] over the past decade. These studies have identified genetic elements at which epigenetic states appear to be inherited through meiosis. The Lamarckian implicati...

Leaving negative ancestors behind

Bacteria with a single cell membrane have evolved from ancestors with two membranes on multiple occasions within the Firmicutes phylum.

Leaving the lysosome behind: novel developments in autophagy inhibition

The search for a single silver bullet for the treatment of cancer has now been overshadowed by the identification of multiple therapeutic targets unique to each malignancy and even to each patient. In recent years, autophagy has emerged as one such therapeutic target. In response to both therapeutic and oncogenic stress, cancer cells upregulate and demonstrate an increased dependence upon this ...

Leaving Parents Behind: Migration and Elderly Living Arrangements in Mexico

Unlike industrialized countries, where parents expect to spend some portion of midto later-life without children at home, traditional patterns of living arrangements in Mexico reflect high levels of family caregiving for the elderly and a high degree of continuity of parent-child coresidence over the lifecourse. Living alone is uncommon due both to structural constraints, fed by economic instab...

The Woes of an Editor